中/英文名称：

肾上腺髓质素受体抗体/ Anti-   ADM R

别名：

Adrenomedullin Receptor L1; 7TMR; ADMR;   adrenomedullin receptor; AM R; AMR; G protein coupled receptor 182; Gamrh;   GPR 182; GPR182; hrhAMR; MGC34399.

产品编号：

zy10028

规格：

0.1ml    0.2ml

抗体来源：

Rabbit

浓    度：

1mg/ml

缓冲液：

0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1%   Sodium azide；Reconstitute with 0.1ml sterile distilled water.

克隆类型：

Polyclonal

亚 型：

IgG

免 疫 原：

KLH conjugated synthetic peptide derived from   mouse ADM R

交叉反应：

Mouse, Rat

状态：

Lyophilized or Liquid

分 子 量：

Predicted molecular weight 45kDa

纯化方法：

affinity purified by Protein A

运输与储存

运输:

The product is shipped at ambient temperature.   Upon receipt, store it immediately at the temperature recommended below.

储存:

Use a manual defrost freezer and avoid repeated   freezethaw cycles.

1 month from date of receipt, 2 to 8℃, reconstituted.

6 months from date of receipt, -20 to -70℃, reconstituted.

12 months from date of receipt, -20 to -70℃as supplied.

When reconstituted in sterile pH 7.4 0.01M PBS or   diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

产品应用

应用:

WB=1:100-500    ELISA=1:500-1000    IP=1:20-100    IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500
  Not yet tested in other applications.
  Optimal working dilutions must be determined by the end user.

背景:

Adrenomedullin is a potent vasodilator peptide   that exerts major effects on cardiovascular function. This gene encodes a seven-transmembrane   protein that belongs to the family 1 of G-protein coupled receptors. Studies   of the rat counterpart suggest that the encoded protein may function as a   receptor for adrenomedullin. [provided by RefSeq, Jul 2008]

其他:

Function:

Orphan receptor.

Subcellular   Location:

Cell membrane; Multi-pass membrane protein.

Tissue   Specificity:

Highly expressed in heart, skeletal muscle,   immune system, adrenal gland and liver.

Similarity:

Belongs to the G-protein coupled receptor 1   family.

Gene   ID:

11318

肾上腺髓质素受体是一个由395个氨基酸组成的，分子中包括七个跨膜区，属G-蛋白家族。在肺部分布丰富。

Tissue/cell:   human lung carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded;
  Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for   15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min;   Blocking buffer (normal goat serum) at 37℃ for 20 min;
  Incubation: Anti-ADM-R Polyclonal Antibody, Unconjugated 1:200, overnight at   4°C, followed by conjugation to the secondary antibody and DAB staining